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Bioengineers have made a breakthrough that will go down in the history of heart failure in the future. Experts have developed the first biohybrid model of human ventricles with spirally aligned beating heart cells. The study found that aligning the muscles actually significantly increased how much blood the ventricle could pump with each contraction.
A GREAT STEP IN MAKING AN ARTIFICIAL HEART!
Heart disease is one of the leading causes of death worldwide. Heart disease, which is partially fatal, unlike other organs, cannot repair itself after an injury. For this reason, the production of an artificial heart, which will involve the wholesale production of a whole human heart for transplantation, is among the most important medical initiatives of the future.
But it is known that building a human heart from scratch is not so easy. To make an artificial heart, scientists need to replicate the unique structures that make up the heart. These structures include repeating spiral geometries that create a twisting motion when the heart beats.
This rotating action of the heart has long been thought to be critical for pumping large volumes of blood and has been difficult to perform, in part because it is difficult to create hearts with different geometries and layouts.
In a recent development, bioengineers at the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS) developed the first biohybrid model of human ventricles with spirally aligned beating heart cells, and in fact developed the first biohybrid model of human ventricles of muscle alignment. .
HEART FAILURE CAN MAKE HISTORY!
This development in artificial heart production, made possible by Focused Rotary Jet Spinning (FRJS), could lead to the realization of full-scale artificial heart production in the future. If these developments in the artificial heart progress, heart failure may soon become a thing of the past. The research in question was published in the journal Science.
“WE ARE APPROACHING THE GOAL OF BUILDING HUMAN HEARTS FOR TRANSPORTATION”
“This work is a major step forward for organ biofabrication and brings us closer to our ultimate goal of building a human heart for transplantation,” Parker, a professor of bioengineering and applied physics, said of the study.
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