Metabolic syndrome is one of the most important public health problems of the 21st century. Metabolic syndrome is defined as a group of diseases in which more than one risk factor for cardiovascular disease accumulates. It is one of the major causes of cardiovascular disease and death in developed countries, although it has become increasingly important in the last century. It is more common in countries with a western lifestyle.
Metabolic syndrome occurs in 34-39% of the adult population in the United States. The incidence of metabolic syndrome in our country is similar to that in Europe and America. To date, many definitions have been developed by various health authorities. Five common components of all definitions; increased fasting blood sugar (insulin resistance), increased blood pressure, increased triglyceride (TG), decreased high density lipoprotein (HDL) and obesity.
UROLOGICAL PROBLEMS ARE MORE COMMON
New research has revealed that the metabolic syndrome is also associated with various urological diseases. Urological problems such as benign prostate enlargement, prostate cancer, kidney cancer, overactive bladder, male infertility, stress urinary incontinence and hypogonadism are more commonly observed in these people.
BEWARE OF SUGAR, HYPERTENSION, OBESITY!
Many studies have shown that there is a strong relationship between metabolic syndrome, cardiovascular disease and erectile dysfunction. The components of the metabolic syndrome also cause vascular inflammation and endothelial dysfunction lining the inner surface of the vessel, and the frequency and severity of erectile dysfunction increases with increasing number of components. They reported that the incidence of varying degrees of erectile dysfunction in patients with metabolic syndrome under the age of 50 was 68.4% and the incidence in patients with metabolic syndrome over 50 was 74.8%.
In our country, any degree of erectile dysfunction was reported in 79% of patients with metabolic syndrome and severe erectile dysfunction in 24.8%. In many studies, metabolic syndrome was found in approximately half of patients over the age of 50 with erectile dysfunction, and approximately half of these patients were found to have severe erectile dysfunction. Various studies have shown that diabetes, hypertension and obesity are the most important components of the metabolic syndrome for the development of severe erectile dysfunction. The hormone testosterone is converted to estrogen in the presence of increased adipose tissue around the abdomen. This can cause sexual dysfunction and sexual resistance. For these reasons, it is stated that erectile dysfunction may be a precursor to future cardiovascular diseases such as atherosclerosis, occlusion, stroke and heart attack.
PROSTATE GROWTH IS VISIBLE
The annual prostate growth rate was found to be higher in men with metabolic syndrome than in men without metabolic syndrome. In these people, urination problems appear at an earlier age. As the number of components of the metabolic syndrome increases, the severity of urinary symptoms increases and the urine flow rate decreases. The response to alpha-blocker therapy, which is the first-line treatment option for patients with a benign prostate, is lower in the presence of metabolic syndrome. In recent years, studies have shown that there may be a link between metabolic syndrome and prostate cancer. In these patients, prostate cancer is said to be more aggressive, and the success rate of cancer and cancer recurrence is higher.
LIFESTYLE IS VERY IMPORTANT
Insulin resistance is the basis of the metabolic syndrome, in which genetic and environmental factors play a role. On the other hand, insulin resistance is a condition of insulin that is unable to enter the cell and transport glucose despite the body’s secretion of insulin. In these cases, when the effect of insulin is insufficient, the amount of fat in the blood and organs increases. The main factors that increase insulin resistance are; Excess weight is caused by a sedentary lifestyle and high calorie intake. After a while, a vicious circle develops between belly fat and insulin resistance. It is necessary to interrupt this cycle with a balanced diet and increase regular physical activity in a medium to high pace. The treatment is based on a Mediterranean diet, avoidance of high-calorie foods and an atherogenic diet, and increased physical activity. It is important to know that drug therapy alone is not enough without changing your lifestyle.